Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.

@article{Dearman2001CharacterizationOA,
  title={Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.},
  author={Rebecca Jane Dearman and Helen Theresa Caddick and Sue Stone and David A Basketter and I A N Kimber},
  journal={Toxicology},
  year={2001},
  volume={167 3},
  pages={217-31}
}
There is a growing interest in the development of methods to characterize the allergenic properties of novel proteins, particularly those expressed by transgenic crop plants. Approaches to the direct evaluation of allergenic potential have focused generally on the ability of proteins to induce antibody (particularly IgE antibody) after systemic (intraperitoneal; i.p.) or gavage administration to high IgE responder strain rodents. To date there has been no systematic comparison of the… CONTINUE READING

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