Characterization of an evolutionarily conserved far-upstream enhancer in the human alpha 2(I) collagen (COL1A2) gene.

Abstract

We have examined the chromatin structure around and upstream of the transcriptional start site of the human alpha2(I) collagen (COL1A2) gene. Four strong DNase I-hypersensitive sites (HS2-5) were only detected in fibroblasts, and a weaker one (HS1) was identified in type I collagen-negative cells. Another hypersensitive site potentially involved in COL1A2… (More)

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@article{Antoniv2001CharacterizationOA, title={Characterization of an evolutionarily conserved far-upstream enhancer in the human alpha 2(I) collagen (COL1A2) gene.}, author={Taras T. Antoniv and Sarah J De Val and D. Wells and Carole Denton and Christian Rabe and Benoit de Crombrugghe and F. Ramirez and George Bou-Gharios}, journal={The Journal of biological chemistry}, year={2001}, volume={276 24}, pages={21754-64} }