Characterization of an Endogenous RNA-Dependent DNA Polymerase Associated with Murine Intracisternal A Particles

@article{Yang1974CharacterizationOA,
  title={Characterization of an Endogenous RNA-Dependent DNA Polymerase Associated with Murine Intracisternal A Particles},
  author={S S Yang and Nelson A. Wivel},
  journal={Journal of Virology},
  year={1974},
  volume={13},
  pages={712 - 720}
}
An RNA-dependent DNA polymerase associated with intracisternal A particles has been characterized. The enzyme required Mg2+ or Mn2+, dithiothreitol and the presence of all four deoxyribonucleoside triphosphates for the expression of maximal activity. Sensitivity of the endogenous RNA-dependent DNA polymerase activity to a low concentration of pancreatic ribonuclease in the presence of a high concentration of NaCl suggested that the enzyme might be utilizing the A particle endogenous RNA as… 
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    Proceedings of the National Academy of Sciences of the United States of America
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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