Characterization of agonist-induced beta-adrenergic receptor-specific desensitization in C62B glioma cells.

@article{Frederich1983CharacterizationOA,
  title={Characterization of agonist-induced beta-adrenergic receptor-specific desensitization in C62B glioma cells.},
  author={Robert C. Frederich and Gary L. Waldo and T. Kendall Harden and John P. Perkins},
  journal={Journal of cyclic nucleotide and protein phosphorylation research},
  year={1983},
  volume={9 2},
  pages={103-18}
}
The characteristics of catecholamine-induced desensitization of the beta-adrenergic receptor-linked adenylate cyclase system is compared in C62B and C6BD12 rat glioma cells and 1321N1 human astrocytoma cells. The process of receptor-specific (or agonist-specific) desensitization is demonstrated in the C62B subline. Thus, upon exposure of C62B cells to… CONTINUE READING