Characterization of age-related changes of tendon stem cells from adult human tendons

@article{Ruzzini2013CharacterizationOA,
  title={Characterization of age-related changes of tendon stem cells from adult human tendons},
  author={Laura Ruzzini and Franca Abbruzzese and Alberto Rainer and Umile Giuseppe Longo and Marcella Trombetta and Nicola Maffulli and Vincenzo Denaro},
  journal={Knee Surgery, Sports Traumatology, Arthroscopy},
  year={2013},
  volume={22},
  pages={2856-2866}
}
The present study evaluated the presence of stem cells in hamstring tendons from adult subjects of different ages. The aim was to isolate, characterize and expand these cells in vitro, and to evaluate whether cell activities are influenced by age. Tendon stem cells (TSCs) were isolated through magnetic sorting from the hamstring tendons of six patients. TSC percentage, morphology and clonogenic potential were evaluated, as well as the expression of specific surface markers. TSC multi-potency… CONTINUE READING
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