Characterization of age‐associated exhausted CD8+ T cells defined by increased expression of Tim‐3 and PD‐1


Aging is accompanied by altered T-cell responses that result in susceptibility to various diseases. Previous findings on the increased expression of inhibitory receptors, such as programmed cell death protein 1 (PD-1), in the T cells of aged mice emphasize the importance of investigations into the relationship between T-cell exhaustion and aging-associated… (More)
DOI: 10.1111/acel.12435


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