Characterization of a two-component regulatory system that regulates succinate-mediated catabolite repression in Sinorhizobium meliloti.

@article{Garcia2010CharacterizationOA,
  title={Characterization of a two-component regulatory system that regulates succinate-mediated catabolite repression in Sinorhizobium meliloti.},
  author={Preston P Garcia and R. M. Bringhurst and Catalina Arango Pinedo and D. Gage},
  journal={Journal of bacteriology},
  year={2010},
  volume={192 21},
  pages={
          5725-35
        }
}
  • Preston P Garcia, R. M. Bringhurst, +1 author D. Gage
  • Published 2010
  • Biology, Medicine
  • Journal of bacteriology
  • When they are available, Sinorhizobium meliloti utilizes C(4)-dicarboxylic acids as preferred carbon sources for growth while suppressing the utilization of some secondary carbon sources such as α- and β-galactosides. The phenomenon of using succinate as the sole carbon source in the presence of secondary carbon sources is termed succinate-mediated catabolite repression (SMCR). Genetic screening identified the gene sma0113 as needed for strong SMCR when S. meliloti was grown in succinate plus… CONTINUE READING
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