Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina.

@article{Fuhrmann2009CharacterizationOA,
  title={Characterization of a transient TCF/LEF-responsive progenitor population in the embryonic mouse retina.},
  author={Sabine Fuhrmann and Amy N Riesenberg and Amber M. Mathiesen and E. Brown and Monica L. Vetter and Nadean L Brown},
  journal={Investigative ophthalmology & visual science},
  year={2009},
  volume={50 1},
  pages={432-40}
}
PURPOSE High mobility group (HMG) transcription factors of the T-cell-specific transcription factor/lymphoid enhancer binding factor (TCF/LEF) family are a class of intrinsic regulators that are dynamically expressed in the embryonic mouse retina. Activation of TCF/LEFs is a hallmark of the Wnt/beta-catenin pathway; however, the requirement for Wnt/beta-catenin and noncanonical Wnt signaling during mammalian retinal development remains unclear. The goal of the study was to characterize more… CONTINUE READING

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