Characterization of a toxin fromParthenium hysterophorus and its mode of excretion in animals

Abstract

Fractionation of methanolic extracts of air dried aerial parts ofParthenium resulted in the isolation of a toxic constituent which was identified as parthenin, the major sesquiterpene lactone from the weed. The LD50 (minimal lethal dose required to cause 50% mortality) for parthenin in rats was 42 mg/kg body weight. When [3H]-parthenin was given orally or… (More)
DOI: 10.1007/BF02702716

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