Characterization of a surface modified dry powder inhalation carrier prepared by "particle smoothing".

@article{Young2002CharacterizationOA,
  title={Characterization of a surface modified dry powder inhalation carrier prepared by "particle smoothing".},
  author={Paul M Young and Daniela Cocconi and P. -E. Colombo and Ruggero Bettini and Robert Price and D. Fraser Steele and Michael J. Tobyn},
  journal={The Journal of pharmacy and pharmacology},
  year={2002},
  volume={54 10},
  pages={1339-44}
}
Atomic force microscopy (AFM) was used to investigate drug-carrier interactions between beclometasone dipropionate (BDP) and a series of untreated and modified lactose surfaces. This quantitative information was correlated with bulk characterization methods and an in-vitro study. Modified lactose surfaces were prepared using a proprietary process referred to as "particle smoothing" to obtain smooth carrier surfaces with or without the presence of magnesium stearate. The engineering of lactose… CONTINUE READING

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