Characterization of a sporulation gene, spoIVA, involved in spore coat morphogenesis in Bacillus subtilis.

@article{Stevens1992CharacterizationOA,
  title={Characterization of a sporulation gene, spoIVA, involved in spore coat morphogenesis in Bacillus subtilis.},
  author={C. M. Stevens and Richard Daniel and N Illing and Jeff Errington},
  journal={Journal of bacteriology},
  year={1992},
  volume={174 2},
  pages={586-94}
}
Mutations in the spoIVA locus of Bacillus subtilis abolish cortex synthesis and interfere with the synthesis and assembly of the spore coat. We have characterized the cloned spoIVA locus in terms of its physical structure and regulation during sporulation. The locus contains a single gene capable of encoding an acidic protein of 492 amino acids (molecular weight, 55,174). The gene is transcribed from a sigma E-dependent promoter soon after the formation of the spore septum. A genetic test… CONTINUE READING