Characterization of a sporozoite antigen common to Plasmodium falciparum and Plasmodium berghei.

Abstract

Previous studies demonstrated that immunization with Plasmodium falciparum sporozoites protected mice against Plasmodium berghei sporozoite infection and that this cross-protection was mediated, at least in part, by anti-sporozoite antibody. The experiments presented in this report show that serum and monoclonal antibodies derived from these protected mice… (More)

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