Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus.

@article{Dbarbouill2009CharacterizationOA,
  title={Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus.},
  author={Michel D{\'e}barbouill{\'e} and Shaynoor Dramsi and Olivier Dussurget and M. A. Nahori and Elisabeth Vaganay and Gr{\'e}gory Jouvion and Alain J. Cozzone and Tarek Msadek and Bertrand Duclos},
  journal={Journal of bacteriology},
  year={2009},
  volume={191 13},
  pages={4070-81}
}
Staphylococcus aureus is a common human cutaneous and nasal commensal and a major life-threatening pathogen. Adaptation to the different environments encountered inside and outside the host is a crucial requirement for survival and colonization. We identified and characterized a eukaryotic-like serine/threonine kinase with three predicted extracellular PASTA domains (SA1063, or Stk1) and its associated phosphatase (SA1062, or Stp1) in S. aureus. Biochemical analyses revealed that Stk1 displays… CONTINUE READING

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