Characterization of a rat alveolar macrophage cell line that expresses a functional mannose receptor.

@article{Lane1998CharacterizationOA,
  title={Characterization of a rat alveolar macrophage cell line that expresses a functional mannose receptor.},
  author={Kirk B. Lane and Brian S. Egan and S L Vick and Rasul Abdolrasulnia and Virginia L. Shepherd},
  journal={Journal of leukocyte biology},
  year={1998},
  volume={64 3},
  pages={345-50}
}
The mannose receptor is a single polypeptide transmembrane glycoprotein expressed on the surface of macrophages that binds and internalizes soluble and particulate ligands. Physiological ligands for this receptor are pathogens, such as mycobacteria, and extracellular acid hydrolases and peroxidases. Expression of the mannose receptor is tightly linked to the functional state of the macrophage: the receptor appears during differentiation, is increased by macrophage deactivating agents, and is… CONTINUE READING
Highly Cited
This paper has 33 citations. REVIEW CITATIONS
15 Citations
35 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains

  • M. E. Tayler, J. T. Conary, M. R. Lennartz, P. D. Stahl, K. Drickamer
  • J. Biol
  • 1990
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…