Characterization of a protein that binds multiple sequences in mammalian type C retrovirus enhancers.

@article{Sun1993CharacterizationOA,
  title={Characterization of a protein that binds multiple sequences in mammalian type C retrovirus enhancers.},
  author={William Sun and Matthew O'Connell and Nancy A Speck},
  journal={Journal of virology},
  year={1993},
  volume={67 4},
  pages={1976-86}
}
Mammalian type C retrovirus enhancer factor 1 (MCREF-1) is a nuclear protein that binds several directly repeated sequences (CNGGN6CNGG) in the Moloney and Friend murine leukemia virus (MLV) enhancers (N. R. Manley, M. O'Connell, W. Sun, N. A. Speck, and N. Hopkins, J. Virol. 67:1967-1975, 1993). In this paper, we describe the partial purification of MCREF-1 from calf thymus nuclei and further characterize the binding properties of MCREF-1. MCREF-1 binds four sites in the Moloney MLV enhancer… CONTINUE READING

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