Characterization of a protein correlated with the production of knob-like protrusions on membranes of erythrocytes infected with Plasmodium falciparum.

@article{Kilejian1979CharacterizationOA,
  title={Characterization of a protein correlated with the production of knob-like protrusions on membranes of erythrocytes infected with Plasmodium falciparum.},
  author={A Z Kilejian},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1979},
  volume={76 9},
  pages={4650-3}
}
  • A Z Kilejian
  • Published 1979 in
    Proceedings of the National Academy of Sciences…
Membranes of erythrocytes infected with Plasmodium falciparum develop protrusions called "knobs." These protrusions are not apparent on erythrocytes infected with young parasites (rings) but develop with the growth of parasites to the trophozoite and schizont stages. The nature and origin of knobs were characterized by comparing the stage-specific proteins of two culture lines of P. falciparum, K+ and K-. K+ parasites produce knobs; K- parasites do not. Erythrocytes infected with both types of… CONTINUE READING