Characterization of a potentially reversible increase in beta-adrenergic receptors in isolated, neonatal rat cardiac myocytes with impaired energy metabolism.

@article{Buja1985CharacterizationOA,
  title={Characterization of a potentially reversible increase in beta-adrenergic receptors in isolated, neonatal rat cardiac myocytes with impaired energy metabolism.},
  author={Luis Maximilian Buja and Kathryn H Muntz and Tamara Rosenbaum and Z Haghani and D K Buja and Anjana Sen and Kenneth R. Chien and James T. Willerson},
  journal={Circulation research},
  year={1985},
  volume={57 4},
  pages={640-5}
}
Previous studies have reported that the numbers of beta- and alpha-adrenergic receptors increase in ischemic myocardium. In vivo studies have raised questions regarding the mechanisms involved in the adrenergic receptor alterations and the consequences of these alterations. The purpose of this study was to evaluate potential relationships among beta-adrenergic receptor changes, high energy phosphate reduction, and severity of cell injury in cultured neonatal rat myocytes treated with metabolic… CONTINUE READING
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INDEX TERMS: 0-Adrenergic receptors

  • S Wallenstein, CL Zucker, JL Fleiss
  • 1980
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