Characterization of a potent inhibitor of platelet aggregation and release reaction isolated from allium sativum (garlic).

@article{Mohammad1986CharacterizationOA,
  title={Characterization of a potent inhibitor of platelet aggregation and release reaction isolated from allium sativum (garlic).},
  author={Syed Mohammad and Stephen C. Woodward},
  journal={Thrombosis research},
  year={1986},
  volume={44 6},
  pages={793-806}
}
When added to platelet-rich plasma, aqueous extracts of garlic inhibited platelet aggregation and the release reaction. Subsequent experiments designed to characterize the inhibitory component revealed that the inhibitory activity was i) associated with small molecular-weight components, ii) the inhibitory component possessed the typical garlic odor and contained an abundance of sulfur, iii) the inhibitory activity could be extracted with organic solvents, and iv) temperatures above 56 degrees… CONTINUE READING

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