Characterization of a posttranslational fucosylation in the growth factor domain of urinary plasminogen activator.

Abstract

A posttranslational modification site in natural and recombinant urinary-type plasminogen activators (urokinases; EC 3.4.21.31) has been localized to Thr-18, in the growth factor domain of the molecule. This is the region of urinary plasminogen activator responsible for its specific receptor binding. An unusual carbohydrate-protein linkage, a single… (More)

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@article{Buko1991CharacterizationOA, title={Characterization of a posttranslational fucosylation in the growth factor domain of urinary plasminogen activator.}, author={Alex M Buko and E J Kentzer and A. M. Petros and Geetha K Menon and Erik R. P. Zuiderweg and V. K. Sarin}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1991}, volume={88 9}, pages={3992-6} }