Characterization of a porcine model of post-operative pain.

  title={Characterization of a porcine model of post-operative pain.},
  author={David Castel and E Willentz and Ofer Doron and Ori Brenner and Sigal Meilin},
  journal={European journal of pain},
  volume={18 4},
BACKGROUND Management of acute pain related to surgical intervention, termed post-operative pain or POP, continues to be a major healthcare challenge. While the rat plantar incision model provides valuable data to researchers about the mechanisms mediating POP, the development of topical and localized treatments in small animal models is limited. To help address these issues, we describe here the characterization of a large animal model of incisional pain. METHODS Pigs underwent full-skin… CONTINUE READING
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