Characterization of a novel type of endogenous activator of soluble guanylyl cyclase.

Abstract

Nitric oxide (NO) remains the only firmly established endogenous modulator of soluble guanylyl cyclase (sGC) activity, but physiological, structural, and biochemical evidence now suggests that in vivo regulation of sGC involves direct interaction with other factors. We searched for such endogenous modulators in human umbilical vein endothelial cells and COS… (More)

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@article{Balashova2005CharacterizationOA, title={Characterization of a novel type of endogenous activator of soluble guanylyl cyclase.}, author={Nataliya Balashova and Fu-Jung Chang and Maria Lamothe and Qian Sun and Annie V Beuve}, journal={The Journal of biological chemistry}, year={2005}, volume={280 3}, pages={2186-96} }