Characterization of a novel oxidase from Thelonectria discophora SANK 18292 involved in nectrisine biosynthesis

Abstract

A fungus, Thelonectria discophora SANK 18292 (JCM 30947), produces nectrisine that has a nitrogen-containing heterocyclic 5-membered ring acting as a glycosidase inhibitor. Our previous study showed the possibility that 4-amino-4-deoxyarabinitol was enzymatically converted to nectrisine but the enzyme was not known. In order to characterize the enzyme… (More)
DOI: 10.1186/s13568-016-0176-1

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