Characterization of a novel mouse monoclonal antibody, clone 1E8.33, highly specific for human procollagen 11A1, a tumor-associated stromal component.

Abstract

A novel IgG1, κ mouse monoclonal antibody (clone 1E8.33) to human procollagen 11A1 has been generated. This antibody is poorly mutated, essentially in germ line configuration; its complementarity determining regions (CDRs) are especially rich in tyrosine and serine residues. The epitope recognized is encompassed in… (More)
DOI: 10.3892/ijo.2012.1360

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@article{GarcaOcaa2012CharacterizationOA, title={Characterization of a novel mouse monoclonal antibody, clone 1E8.33, highly specific for human procollagen 11A1, a tumor-associated stromal component.}, author={Marcos Garc{\'i}a-Oca{\~n}a and Fernando V{\'a}zquez and Carmen Garc{\'i}a-Pravia and Nelson Fuentes-Mart{\'i}nez and Primitiva Men{\'e}ndez-Rodr{\'i}guez and Florentino Fresno-Forcelledo and Luis Barneo-Serra and Jokin Del Amo-Iribarren and Laureano Sim{\'o}n-Buela and Juan Ram{\'o}n de Los Toyos}, journal={International journal of oncology}, year={2012}, volume={40 5}, pages={1447-54} }