Characterization of a novel human cell-cycle-regulated homologue of Drosophila dlg1.

@article{Bassal2001CharacterizationOA,
  title={Characterization of a novel human cell-cycle-regulated homologue of Drosophila dlg1.},
  author={Sahar Bassal and Nobuo Nomura and Dj Venter and Karsten Brand and Malcolm McKay and Peter J van der Spek},
  journal={Genomics},
  year={2001},
  volume={77 1-2},
  pages={
          5-7
        }
}
Cell cycle defects have been associated with the process of carcinogenesis in many studies. Here we report the cloning and analysis of the novel gene KIAA0008 (GenBank acc. no. D13633). Chromosomal localization experiments assigned the gene to chromosome 14q22-q23. The mRNA transcript was found to be cell cycle regulated, expressed at S-phase, and maintained at both G2-and M-phases. In situ hybridization showed expression in proliferating colon and breast (tumor) tissues. Structurally, KIAA0008… CONTINUE READING

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KIAA0008 gene is associated with invasive phenotype of human hepatocellular carcinoma—a functional analysis

  • Journal of Cancer Research and Clinical Oncology
  • 2004
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