Characterization of a novel glucosamine-6-phosphate deaminase from a hyperthermophilic archaeon.

@article{Tanaka2005CharacterizationOA,
  title={Characterization of a novel glucosamine-6-phosphate deaminase from a hyperthermophilic archaeon.},
  author={Toshiyuki Tanaka and Fumikazu Takahashi and Toshiaki Fukui and Shinsuke Fujiwara and Haruyuki Atomi and T. Imanaka},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 20},
  pages={7038-44}
}
A key step in amino sugar metabolism is the interconversion between fructose-6-phosphate (Fru6P) and glucosamine-6-phosphate (GlcN6P). This conversion is catalyzed in the catabolic and anabolic directions by GlcN6P deaminase and GlcN6P synthase, respectively, two enzymes that show no relationship with one another in terms of primary structure. In this study, we examined the catalytic properties and regulatory features of the glmD gene product (GlmD(Tk)) present within a chitin degradation gene… CONTINUE READING