Characterization of a novel bile-inducible operon encoding a two-component regulatory system in Lactobacillus acidophilus.

@article{Pfeiler2007CharacterizationOA,
  title={Characterization of a novel bile-inducible operon encoding a two-component regulatory system in Lactobacillus acidophilus.},
  author={Erika A Pfeiler and M Andrea Azcarate-Peril and Todd R. Klaenhammer},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 13},
  pages={4624-34}
}
Lactobacillus acidophilus NCFM is an industrially important strain used extensively as a probiotic culture. Tolerance of the presence of bile is an attribute important to microbial survival in the intestinal tract. A whole-genome microarray was employed to examine the effects of bile on the global transcriptional profile of this strain, with the intention of elucidating genes contributing to bile tolerance. Genes involved in carbohydrate metabolism were generally induced, while genes involved… CONTINUE READING

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