Characterization of a novel bacterial arginine kinase from Desulfotalea psychrophila.

  title={Characterization of a novel bacterial arginine kinase from Desulfotalea psychrophila.},
  author={Logan D. Andrews and J Graham and Mark J Snider and Dean Fraga},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry \& molecular biology},
  volume={150 3},
  • L. AndrewsJ. Graham D. Fraga
  • Published 1 July 2008
  • Biology
  • Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology

Identification and Characterization of a Putative Arginine Kinase Homolog from Myxococcus xanthus Required for Fruiting Body Formation and Cell Differentiation

This study biochemically purified and characterized a putative M. xanthus arginine kinase, Ark, and demonstrated that it has retained the ability to catalyze the phosphorylation ofArginine by using ATP, and constructed a null mutation in the ark gene and demonstrated its role in both certain stress responses and development.

Characterization and origin of bacterial arginine kinases.

Bacterial arginine kinases have a highly skewed distribution within the proteobacteria.

Arginine kinase from Myzostoma cirriferum, a basal member of annelids.

Arginine Kinase from the Tardigrade, Macrobiotus occidentalis: Molecular Cloning, Phylogenetic Analysis and Enzymatic Properties

The phylogenetic trees of 104 AKs indicated clearly that Macrobiotus AK (from the phylum Tardigrada) shows close affinity with Epiperipatus and Euperipatoides AKs, and therefore forms a sister group with the arthropod AKs.

Characterization of the arginine kinase isoforms in Caenorhabditis elegans.

Cooperativity and evolution of Tetrahymena two-domain arginine kinase.



The Early Evolution of the Phosphagen Kinases—Insights from Choanoflagellate and Poriferan Arginine Kinases

Evidence is provided suggesting that the initial gene duplication event(s) leading to the CK lineage may have occurred before the divergence of the choanoflagellate and animal lineages.

Trypanosoma cruzi Arginine Kinase Characterization and Cloning

The finding in the parasite of a phosphagen and its biosynthetic pathway, which are totally different from those in mammalian host tissues, points out this arginine kinase as a possible chemotherapy target for Chagas' disease.

Evolution of the Cytoplasmic and Mitochondrial Phosphagen Kinases Unique to Annelid Groups

The intron/exon organization of the genes for the following phosphagen kinases, including Eisenia LK, Sabellastarte AK, and Arenicola mitochondrial TK (MiTK), are determined, supporting the view that the MiCK gene is basal and ancestral to the phosphagenKinases unique to annelids.

The genome of Desulfotalea psychrophila, a sulfate-reducing bacterium from permanently cold Arctic sediments.

The genome sequence of D. psychrophila strain LSv54 is described, which consists of a 3 523 383 bp circular chromosome with 3118 predicted genes and two plasmids of 121 586 bp and 14 663 bp, which encodes more than 30 two-component regulatory systems.

Role of Amino Acid Residues on the GS Region of Stichopus Arginine Kinase and Danio Creatine Kinase

The results suggested that the Ile69 to Gly mutant, displaying a high Kmcr and a low Vmax, plays an important role in Creatine-binding, consistent with the observation that in the structure of Torpedo CK, Ile 69 provides a hydrophobic pocket to optimize creatine-binding.

The role of phosphagen specificity loops in arginine kinase

An atomic structure of the mismatched complex of arginine kinase with creatine and ADP indicates that specificity can also be mediated by an active site that allows substrate prealignment that is optimal for reactivity only with cognate substrates and not with close homologs that bind but do not react.

Purification and characterization of arginine kinase from the American cockroach (Periplaneta americana).

The availability of pure protein, its characterization and potential regulation of activity, will be useful in developing agents to control the cockroach population and its destructive role in agriculture and human health.