Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.


CPD-N is a cytokine-inducible CPD (carboxypeptidase-D) isoform identified in rat Nb2 T-lymphoma cells. The prototypic CPD (180 kDa) has three CP domains, whereas CPD-N (160 kDa) has an incomplete N-terminal domain I but intact domains II and III. CPD processes polypeptides in the TGN (trans-Golgi network) but the Nb2 CPD-N is nuclear. The present study… (More)


12 Figures and Tables

Slides referencing similar topics