Characterization of a near-infrared fluorescent DCPO-tagged glucose analogue for cancer cell imaging.

@article{Fang2017CharacterizationOA,
  title={Characterization of a near-infrared fluorescent DCPO-tagged glucose analogue for cancer cell imaging.},
  author={Yanfen Fang and Wanli Zhang and Mengli Zhu and Shiguang Chen and Xuan Liu and Wei Lu and Xiongwen Zhang},
  journal={Journal of photochemistry and photobiology. B, Biology},
  year={2017},
  volume={166},
  pages={
          264-271
        }
}
Cancer cells are usually characterized with an increase in glucose uptake when compared with normal cells, which is known as Warburg effect. Near-infrared (NIR) fluorescent glucose analogues have been previously synthesized and been applied in cancer cell imaging. However, most NIR dyes usually have one or more charge in their structures, which may cause low cell membrane permeability and hamper their application in cell imaging. Here we reported a novel glucose analogue N2, which was designed… CONTINUE READING
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