Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine.

@article{Hilfiker1998CharacterizationOA,
  title={Characterization of a murine type II sodium-phosphate cotransporter expressed in mammalian small intestine.},
  author={Helene Hilfiker and Olaf Hattenhauer and Martin Traebert and Irmgard Forster and Heini Murer and Juerg Biber},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 24},
  pages={
          14564-9
        }
}
An isoform of the mammalian renal type II Na/Pi-cotransporter is described. Homology of this isoform to described mammalian and nonmammalian type II cotransporters is between 57 and 75%. Based on major diversities at the C terminus, the new isoform is designed as type IIb Na/Pi-cotransporter. Na/Pi-cotransport mediated by the type IIb cotransporter was studied in oocytes of Xenopus laevis. The results indicate that type IIb Na/Pi-cotransport is electrogenic and in contrast to the renal type II… CONTINUE READING

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