Characterization of a monoclonal antibody (A12) that defines a human acute lymphoblastic leukemia-associated differentiation antigen.

@article{Carrel1983CharacterizationOA,
  title={Characterization of a monoclonal antibody (A12) that defines a human acute lymphoblastic leukemia-associated differentiation antigen.},
  author={Stefan Carrel and Didier Heumann and Rafick Pierre S{\'e}kaly and P. Zaech and Franz Buchegger and Ch. Girardet},
  journal={Hybridoma},
  year={1983},
  volume={2 2},
  pages={
          149-60
        }
}
A human leukemia-associated differentiation antigen has been identified by a monoclonal antibody (A12) raised to the lymphoblastoid cell line NALM-1. The A12 antigen was expressed on the surface of leukemic cells from patients with common acute lymphoblastic leukemia (c-ALL) as well as on cells of the hematopoietic cell lines NALM-1, Reh-6, Raji, Daudi, CEM, and 8402 as determined by an antibody-binding radioimmunoassay, as well as by indirect immunofluorescence and FACS analysis. This antigen… CONTINUE READING
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