Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis

  title={Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis},
  author={Lingling Liu and J. Zhang and J. Yuan and Yongjun Dang and Chenyi Yang and X. Chen and Jianing Xu and L. Yu},
  journal={Molecular Biology Reports},
  • Lingling Liu, J. Zhang, +5 authors L. Yu
  • Published 2004
  • Biology, Medicine
  • Molecular Biology Reports
  • AbstractProtein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R, an EF-hand Ca2+ binding protein, contains four high-affinity EF-hand calcium-binding sites, indicating that PPP3 plays critical roles in many calcium-mediated signal transduction pathways. PPP3R has two isoforms, PPP3R1 (also known as PP2Bβ1) and PPP3R2 (also… CONTINUE READING
    22 Citations
    Partial Inhibition of Calcineurin Activity by Rcn2 as a Potential Remedy for Vps13 Deficiency
    Calcineurin tax-6 regulates male ray development and counteracts with kin-29 kinase in Caenorhabditis elegans
    Direct Evidence for Calcineurin Binding to the Exon-7 Loop of the Sodium-Bicarbonate Cotransporter NBCn1
    • 3
    • PDF
    Molecular analysis of CIB4 gene and protein in Kermani sheep
    • 7
    • Highly Influenced
    • PDF
    Calcineurin Links Mitochondrial Elongation with Energy Metabolism.
    • 42
    • Highly Influenced
    Calcineurin is required for male sex pheromone biosynthesis and female acceptance
    • 6


    Regulation of the Calmodulin-stimulated Protein Phosphatase, Calcineurin*
    • 854
    • PDF
    Calcineurin: not just a simple protein phosphatase.
    • D. Guerini
    • Biology, Medicine
    • Biochemical and biophysical research communications
    • 1997
    • 144