Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis
@article{Liu2004CharacterizationOA, title={Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis}, author={Lingling Liu and Jianxuan Zhang and Jian-Li Yuan and Yongjun Dang and Chenyi Yang and Xiujuan Chen and Jianing Xu and Long Yu}, journal={Molecular Biology Reports}, year={2004}, volume={32}, pages={41-45} }
AbstractProtein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R, an EF-hand Ca2+ binding protein, contains four high-affinity EF-hand calcium-binding sites, indicating that PPP3 plays critical roles in many calcium-mediated signal transduction pathways. PPP3R has two isoforms, PPP3R1 (also known as PP2Bβ1) and PPP3R2 (also…
28 Citations
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