Characterization of a highly divergent TT virus genome.

  title={Characterization of a highly divergent TT virus genome.},
  author={R L Hallett and Jonathan P. Clewley and F Bobet and Patrick J Mckiernan and Chong Gee Teo},
  journal={The Journal of general virology},
  volume={81 Pt 9},
A novel TT virus (TTV)-like DNA sequence was detected in the serum of a patient (PM) with acute non-A-E hepatitis. The full-length genome sequence, referred to here as PM virus (PMV), was obtained and its relationship to other full or near full-length TTV sequences examined. Although it shares a common genomic arrangement and short conserved regions, the majority of the genome is extremely divergent, displaying an average genetic distance of 0.60 from all other TTV sequences. By comparing PMV… CONTINUE READING


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