Characterization of a hepatitis B and hepatitis delta virus receptor binding site.

@article{Engelke2006CharacterizationOA,
  title={Characterization of a hepatitis B and hepatitis delta virus receptor binding site.},
  author={Matthias Engelke and Kerry Mills and Stefan Martin Seitz and Petra Simon and Philippe Gripon and Martina Schnoelzer and Stephan Urban},
  journal={Hepatology},
  year={2006},
  volume={43 4},
  pages={750-60}
}
Insights into the early infection events of the human hepatitis B (HBV) and hepatitis delta virus (HDV) have been limited because of the lack of a cell culture system supporting the full replication cycle for these important pathogens. The human hepatoma cell line HepaRG allows the experimental induction of a differentiated state, thereby gaining susceptibility toward HBV and HDV infection. We recently identified HBV envelope protein-derived lipopeptides comprising amino acids 2 though 48 of… CONTINUE READING
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