Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisus.

@article{Istivan2004CharacterizationOA,
  title={Characterization of a haemolytic phospholipase A(2) activity in clinical isolates of Campylobacter concisus.},
  author={Taghrid Istivan and Peter J. Coloe and Benjamin N Fry and Peter L. Ward and Stuart C. Smith},
  journal={Journal of medical microbiology},
  year={2004},
  volume={53 Pt 6},
  pages={483-93}
}
A membrane-bound, haemolytic phospholipase A(2) (PLA(2)) activity was detected in clinical strains of Campylobacter concisus isolated from children with gastroenteritis. The clinical strains were assigned into two molecular groups (genomospecies) based on PCR amplification of their 23S rDNA. This calcium-dependent, heat-stable, haemolytic PLA(2) activity was detected in strains from both genomospecies. A crude haemolysin extract (CHE) was initially prepared from cellular outer-membrane proteins… CONTINUE READING