Characterization of a galectin-like activity from the parasitic nematode, Haemonchus contortus, which modulates ovine eosinophil migration in vitro.

@article{Turner2008CharacterizationOA,
  title={Characterization of a galectin-like activity from the parasitic nematode, Haemonchus contortus, which modulates ovine eosinophil migration in vitro.},
  author={Darryl G. Turner and Louise A Wildblood and Neil F. Inglis and Douglas G Jones},
  journal={Veterinary immunology and immunopathology},
  year={2008},
  volume={122 1-2},
  pages={138-45}
}
The development of eosinophilia is a characteristic feature of helminth infection, although the exact nature of the interaction between eosinophils and parasites remains to be fully defined. Previously, it has been reported that Haemonchus contortus and other nematodes produce eosinophil-specific chemoattractants. This paper describes studies aimed at isolating and identifying the factor(s) responsible. Initial studies showed that soluble extracts of infective larvae (L3) of H. contortus… CONTINUE READING