Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis.

@article{Schmainda2004CharacterizationOA,
  title={Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis.},
  author={Kathleen M. Schmainda and S D Rand and Allen M Joseph and Rebecca Lund and Benjamin D Ward and Arvind P. Pathak and John L. Ulmer and Michael A Badruddoja and Hendrikus G. J. Krouwer},
  journal={AJNR. American journal of neuroradiology},
  year={2004},
  volume={25 9},
  pages={1524-32}
}
BACKGROUND AND PURPOSE No widespread clinical method provides specific information about the angiogenic characteristics of gliomas. We characterized blood volume and vascular morphologic parameters from combined gradient-echo (GE) and spin-echo (SE) MR imaging and assessed their relationship to tumor grade, a known correlate of glioma angiogenesis. METHODS Simultaneous GE and SE echo-planar imaging was performed with bolus gadolinium administration (0.20-0.25 mmol/kg) in 73 patients with… CONTINUE READING