Characterization of a family of glycoproteins associated with the bile canalicular membrane of normal hepatocytes but not expressed by two transplantable rat hepatocellular carcinomas.

@article{Hixson1983CharacterizationOA,
  title={Characterization of a family of glycoproteins associated with the bile canalicular membrane of normal hepatocytes but not expressed by two transplantable rat hepatocellular carcinomas.},
  author={Douglas C. Hixson and James P Allison and J E Chesner and M J Leger and L L Ridge and E F Walborg},
  journal={Cancer research},
  year={1983},
  volume={43 8},
  pages={3874-84}
}
Xenoantisera were used to investigate the expression of normal cell-surface components on transplantable rat hepatocellular carcinoma (253 and 311c) cells. Cell-surface components, immunoprecipitated from non-ionic detergent extracts of 125I-labeled hepatocytes by xenoantisera raised against rat hepatocytes, 253 cells, or 311c cells, were analyzed by 2-dimensional polyacrylamide gel electrophoresis. Comparison of the gel patterns revealed that anti-hepatocyte antiserum was reactive with a… CONTINUE READING