Characterization of a eukaryotic type serine/threonine kinase in Spodoptera litura nucleopolyhedrovirus-I (SpltNPV-I).

@article{Mishra2007CharacterizationOA,
  title={Characterization of a eukaryotic type serine/threonine kinase in Spodoptera litura nucleopolyhedrovirus-I (SpltNPV-I).},
  author={Gourav Mishra and Rakha Hari Das},
  journal={Virus research},
  year={2007},
  volume={128 1-2},
  pages={
          126-34
        }
}
An open reading frame (ORF) of 819nt coding for a predicted protein of 272 amino acids was identified in the genome of Spodoptera litura nucleopolyhedrovirus (SpltNPV-I). Sequence derived amino acid sequence analysis of this ORF suggested it to be a eukaryotic type protein kinase having conserved I-XI subdomains of Hanks kinase. In addition to kinase catalytic domains, this hypothetical protein had two bromodomains which could play regulatory roles in transcription. The ORF was expressed as… CONTINUE READING