Characterization of a distinct plasma membrane macrodomain in differentiated adipocytes.

  title={Characterization of a distinct plasma membrane macrodomain in differentiated adipocytes.},
  author={Robert G. Parton and Juan Carlos Molero and Matthias Floetenmeyer and Kathryn M. Green and David E. James},
  journal={The Journal of biological chemistry},
  volume={277 48},
Caveolae are small invaginations of the cell surface that are abundant in mature adipocytes. A recent study (Kanzaki, M., and Pessin, J. E. (2002) J. Biol. Chem. 277, 25867-25869) described novel caveolin- and actin-containing structures associated with the adipocyte cell surface that contain specific signaling proteins. We have characterized these structures, here termed "caves," using light and electron microscopy and observe that they represent surface-connected wide invaginations of the… CONTINUE READING

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