Characterization of a cyclooxygenase-2-765G-->C promoter polymorphism in human neural cells.

Abstract

Direct sequencing of the human cyclooxygenase-2 gene promoter revealed a common single nucleotide substitution, cyclooxygenase-2-765G-->C, in 24.5% of the populations analyzed. This change introduced a 20 base pair polypyrimidine/polypurine element and a partial recognition feature for RXRalpha, the 9-cis retinoic acid receptor, into the polymorphic… (More)

Topics

Cite this paper

@article{Cui2005CharacterizationOA, title={Characterization of a cyclooxygenase-2-765G-->C promoter polymorphism in human neural cells.}, author={J. Cui and Shabnam Salehi-Rad and Ekaterina A. Rogaeva and Walter J. Lukiw}, journal={Neuroreport}, year={2005}, volume={16 6}, pages={575-9} }