Characterization of a closed femur fracture model in mice.

@article{Manigrasso2004CharacterizationOA,
  title={Characterization of a closed femur fracture model in mice.},
  author={Michaele Beth Manigrasso and James Patrick O'Connor},
  journal={Journal of orthopaedic trauma},
  year={2004},
  volume={18 10},
  pages={
          687-95
        }
}
OBJECTIVES The goal of this study was to develop and characterize a closed femur fracture model for mice that can be used for the molecular and genetic analysis of fracture healing. STUDY DESIGN Longitudinal time study of species-specific fracture healing. METHODS A protocol was developed for creating reproducible, closed femur fractures in mice. Impending fractures were stabilized by retrograde insertion of a 0.01-inch-diameter, stainless steel wire into the intramedullary canal. The… CONTINUE READING
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