Characterization of a closed femur fracture model in mice.

  title={Characterization of a closed femur fracture model in mice.},
  author={Michaele Beth Manigrasso and James Patrick O'Connor},
  journal={Journal of orthopaedic trauma},
  volume={18 10},
OBJECTIVES The goal of this study was to develop and characterize a closed femur fracture model for mice that can be used for the molecular and genetic analysis of fracture healing. STUDY DESIGN Longitudinal time study of species-specific fracture healing. METHODS A protocol was developed for creating reproducible, closed femur fractures in mice. Impending fractures were stabilized by retrograde insertion of a 0.01-inch-diameter, stainless steel wire into the intramedullary canal. The… CONTINUE READING
Highly Cited
This paper has 107 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 57 citations

107 Citations

Citations per Year
Semantic Scholar estimates that this publication has 107 citations based on the available data.

See our FAQ for additional information.