Characterization of a class of cationic proteins that specifically interact with intermediate filaments.

@article{Steinert1981CharacterizationOA,
  title={Characterization of a class of cationic proteins that specifically interact with intermediate filaments.},
  author={Peter M. Steinert and J S Cantieri and David C. Teller and John D Lonsdale-Eccles and Beverly A. Dale},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1981},
  volume={78 7},
  pages={4097-101}
}
We describe a class of cationic structural proteins that associate specifically with intermediate filaments (IF) but not with other types of cytoskeletal proteins. These proteins, for which the term filaggrin is introduced, are isolated from the stratum corneum of mammalian epidermis. They are species-distinct proteins; for example, rat and mouse filaggrin have different molecular weights and amino acid compositions, but are nevertheless chemically and functionally ver similar. They interact in… CONTINUE READING

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