Characterization of a bacteriocin produced by Prevotella nigrescens ATCC 25261.

  title={Characterization of a bacteriocin produced by Prevotella nigrescens ATCC 25261.},
  author={Jasadee Kaewsrichan and Charles William Ian Douglas and Jon Nissen-Meyer and Gunnar Fimland and Rawee Teanpaisan},
  journal={Letters in applied microbiology},
  volume={39 5},
AIMS To characterize the antimicrobial activity produced by Prevotella nigrescens ATCC 25261, and to evaluate its safety on cultured gingival fibroblasts. METHODS AND RESULTS An antimicrobial activity was obtained from purifying the culture supernatant of Pr. nigrescens ATCC 25261. Purification of the active compound was achieved with ammonium sulphate precipitation followed by anion-exchange and gel filtration chromatography. As revealed by SDS-PAGE, the active fraction was relatively… CONTINUE READING


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