Characterization of a Shiga toxin 1-neutralizing recombinant Fab fragment isolated by phage display system.

Abstract

Shiga toxin (Stx)-producing Escherichia coli (STEC) causes bloody diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome. Molecular structural analysis of Stx-neutralizing monoclonal antibody (mAb) will be helpful for development of therapeutics and prophylactics for STEC infection. In this study, we cloned the genes of Stx 1-neutralizing mAb, termed… (More)

Topics

4 Figures and Tables

Slides referencing similar topics