Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

@article{Rota2003CharacterizationOA,
  title={Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome},
  author={Paul A. Rota and M. Steven Oberste and Stephan S Monroe and William Allan Nix and Raymond P. Campagnoli and Joseph Icenogle and Silvia Peñaranda and Bettina Bankamp and Kaija Maher and Min-Hsin Chen and Suxiong Tong and Azaibi Tamin and Luis E. Lowe and Michael Frace and Joseph L. Derisi and Qi Chen and David Wang and Dean D Erdman and Teresa C.T. Peret and Cara C. Burns and Thomas G. Ksiazek and Pierre E Rollin and Anthony Michel Jean Sanchez and Stephanie L. Liffick and Brian P. Holloway and Josef R Limor and Karen A. McCaustland and Melissa A. Olsen-Rasmussen and Ron A. M. Fouchier and Stephan G{\"u}nther and Albert D M E Osterhaus and Christian Drosten and Mark A. Pallansch and Larry J. Anderson and William J. Bellini},
  journal={Science},
  year={2003},
  volume={300},
  pages={1394 - 1399}
}
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS… 
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