Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

@article{Rota2003CharacterizationOA,
  title={Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome},
  author={P. Rota and M. Oberste and S. Monroe and W. A. Nix and R. Campagnoli and J. Icenogle and S. Peñaranda and B. Bankamp and K. Maher and Min-hsin Chen and Suxiong Tong and A. Tamin and Luis E. Lowe and M. Frace and J. Derisi and Qi Chen and David G. Wang and D. Erdman and T. Peret and C. Burns and T. Ksiazek and P. Rollin and A. Sanchez and S. Liffick and B. Holloway and J. Limor and K. McCaustland and M. Olsen-Rasmussen and R. Fouchier and S. G{\"u}nther and A. Osterhaus and C. Drosten and M. Pallansch and L. Anderson and W. Bellini},
  journal={Science},
  year={2003},
  volume={300},
  pages={1394 - 1399}
}
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratorysyndrome (SARS). The sequence of the complete genome of SARS-CoV was determined, and the initial characterization of the viral genome is presented in this report. The genome of SARS-CoV is 29,727 nucleotides in length and has 11 open reading frames, and its genome organization is similar to that of other coronaviruses. Phylogenetic analyses and sequence comparisons showed that SARS… Expand

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