Characterization of a New Human Cell Line (CH-3573) Derived from a Grade II Chondrosarcoma with Matrix Production

@article{CalabuigFarias2012CharacterizationOA,
  title={Characterization of a New Human Cell Line (CH-3573) Derived from a Grade II Chondrosarcoma with Matrix Production},
  author={S{\'i}lvia Calabuig-Fari{\~n}as and Rosario Gil Benso and K{\'a}roly Szuhai and Isidro Machado and J{\'o}se Antonio L{\'o}pez-Guerrero and Danielle de Jong and Amando Peydr{\'o} and Teresa San Miguel and L. Barranco Navarro and Antonio Pell{\'i}n and Antonio Llombart-Bosch},
  journal={Pathology & Oncology Research},
  year={2012},
  volume={18},
  pages={793-802}
}
Chondrosarcomas are malignant cartilage-forming tumors that represent the third most common malignant solid tumor of bone. In patients with grades II and III, local recurrence, increasing tumor size and dedifferentiation have been associated with lower survival rates. These biologically poorly-understood neoplasms vary considerably in clinical presentation and biological behavior. Cytogenetic studies have shown that heterogeneity is related to karyotypic complexity; moreover, alterations in the… CONTINUE READING
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