Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.

Abstract

A screen for Mycobacterium tuberculosis (Mtb) mutants sensitive to reactive nitrogen intermediates identified transposon insertions in the presumptive proteasomal ATPase gene mpa (mycobacterium proteasome ATPase; Rv2115c). mpa mutants are attenuated in both wild type and nitric oxide synthase 2 deficient mice. In this work, we show that attenuation of mpa… (More)

Topics

Cite this paper

@article{Darwin2005CharacterizationOA, title={Characterization of a Mycobacterium tuberculosis proteasomal ATPase homologue.}, author={K. Heran Darwin and Gang Lin and Zhiqiang Chen and Huilin Li and Carl Nathan}, journal={Molecular microbiology}, year={2005}, volume={55 2}, pages={561-71} }