Characterization of a B cell helper factor(s) derived from CD5+ B cell hybridomas.

Abstract

Work from our laboratory suggests that the selective advantage of frequently autoreactive CD5+ B cells is to provide activation signals to CD5- antigen-specific B cells. This hypothesis is supported by the observation that supernatants from CD5+ B cell hybridomas replace CD5+ B cell populations in helping idiotypic B cell subsets respond to antigen plus… (More)

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@article{Hardin1990CharacterizationOA, title={Characterization of a B cell helper factor(s) derived from CD5+ B cell hybridomas.}, author={J. Hardin and M. Gibson and Y. Kawano and Stephen P. Spielberg and C. Mart{\'i}n and M. Collins and M. E. Dorf and David H. Sherr}, journal={Cellular immunology}, year={1990}, volume={126 2}, pages={304-21} }