Characterization of a 25-pS nonselective cation channel in a cultured secretory epithelial cell line

@article{Cook1990CharacterizationOA,
  title={Characterization of a 25-pS nonselective cation channel in a cultured secretory epithelial cell line},
  author={David I. Cook and Philip Poronnik and John Atherton Young},
  journal={The Journal of Membrane Biology},
  year={1990},
  volume={114},
  pages={37-52}
}
We have studied a 25-pS nonselective cation channel from the apical membranes of cell line ST885, derived from neonatal mouse mandibular glands. Its Cl− permeability was not significantly different from zero. The permeabilities (relative to Na+) for inorganic cations were NH 4 + (1.87)>K+(1.12)>Li+ (1.02)>Na+(1)>Rb+(0.81)>Mg2+(0.07)>Ca2+(0.002), and for organic cations, guanidinium (1.61)<ethanolamine (0.70)>4-aminopyridine (0.66)>diethylamine (0.54)>piperazine (0.25)>Tris (0.18)>N… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 42 references

The permeability of the endplate channel to organic cations in frog muscle

The Journal of general physiology • 1980
View 5 Excerpts
Highly Influenced

Electrolyte Solutions. (2 nd Ed

R. A. Robinson, R. H. Stokes
1965
View 4 Excerpts
Highly Influenced

Ion channels in pancreatic duct cells and their role in bicarbonate secretion

M. A. Gray, J. R. Greenwell, B. E. Argent
Exocrine Secretion • 1988
View 5 Excerpts
Highly Influenced

Single calcium-dependent cation channels in mouse pancreatic acinar cells

The Journal of Membrane Biology • 1984
View 4 Excerpts
Highly Influenced

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